50% of the time I can walk to the user's workstation and ask them to do what they did before while I watch over their shoulder, and lo and behold, it doesn't happen again.
"I've tried to rename this file like ten times and it won't let me do it. So I tried to move it to another folder and it won't let me do that Either!"
"May I have your chair so I can get to the keyboard?"
I minimize umpteen different windows open and I arrive at a document.
"What was the file name of that document you were trying to rename?"
"It was xxxdlf.AIA.effing. contract.doc.doc."
"Let me close this and let's see if it works now."
"Oh! It worked! That's so Weird!"
"You had the file open."
"You have a voter's registration card, don't you."